Tag » Spermatogenesis

Male Birth Control: More Than Just Condoms

As women living in the 21th century, you’ve probably heard men joke that a condom is their 25-cent insurance policy that prevents 18-plus years of parental responsibility, but how did that happen? 597 kata lagi

Transcription initiation codes at developmental transitions

The initiation of transcription at appropriate sites in the genome is critical for development and yet few rules governing selection are known and no core promoter element has so far been assigned a specific role in development. 102 kata lagi

Histone Modifications

*G.B. Danks, *P. Navratilova, B. Lenhard, and E.M. Thompson. Distinct Core Promoter Codes Drive Transcription Initiation at Key Developmental Transitions in a Marine Chordate. Preprint out on bioRxiv.

doi: https://doi.org/10.1101/140764

Abstract

Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component of this and yet few rules governing selection are known. 210 kata lagi

Publication

*P. Navratilova, *G.B. Danks, A. Long, S. Butcher, J.R. Manak, and E.M. Thompson. Sex-specific chromatin landscapes in an ultra-compact chordate genome. Epigenetics and Chromatin, 10(1), 2017.

DOI 10.1186/s13072-016-0110-4

Abstract

Background: In multicellular organisms, epigenome dynamics are associated with transitions in the cell cycle, development, germline speci cation, gametogenesis and inheritance. Evolutionarily, regulatory space has increased in complex metazoans to accommodate these functions. 228 kata lagi

Publication