Tag » Spermatogenesis

Transcription initiation codes at developmental transitions

The initiation of transcription at appropriate sites in the genome is critical for development and yet few rules governing selection are known and no core promoter element has so far been assigned a specific role in development. 102 kata lagi

Histone Modifications

*G.B. Danks, *P. Navratilova, B. Lenhard, and E.M. Thompson. Distinct Core Promoter Codes Drive Transcription Initiation at Key Developmental Transitions in a Marine Chordate. Preprint out on bioRxiv.

doi: https://doi.org/10.1101/140764


Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component of this and yet few rules governing selection are known. 210 kata lagi


*P. Navratilova, *G.B. Danks, A. Long, S. Butcher, J.R. Manak, and E.M. Thompson. Sex-specific chromatin landscapes in an ultra-compact chordate genome. Epigenetics and Chromatin, 10(1), 2017.

DOI 10.1186/s13072-016-0110-4


Background: In multicellular organisms, epigenome dynamics are associated with transitions in the cell cycle, development, germline speci cation, gametogenesis and inheritance. Evolutionarily, regulatory space has increased in complex metazoans to accommodate these functions. 228 kata lagi


Causes of zero sperm count

A man’s fertility generally relies on the quantity and quality of his sperm. If the number of sperm a man ejaculates is low or if the sperm are of a poor quality or zero sperm count, it will be difficult, and sometimes impossible, for him to cause a pregnancy. 19 kata lagi


SpermHope Kit - New supportive treatment for azoospermia

SpermHope Kit is a new supportive treatment for azoospermia. This treatment is for men who are found to have primary testicular failure usually cannot be fully cure and will likely require the use of surgical sperm retrieval methods to recover viable sperm for IVF. 23 kata lagi


Non-obstructive azoospermia - Men infertility

Non-obstructive azoospermia (NOA) is a severe form of infertility accounting for 10% of infertile men. Microdissection testicular sperm extraction (microTESE) includes a set of clinical protocols from which viable sperm are collected from patients (suffering from NOA), for intracytoplasmic sperm injection (ICSI). 56 kata lagi


Catching up

Just emerging from a busy teaching period, it was as ever a pleasure this year to welcome first another enthusiastic group of Bachelor students to our upper-level undergraduate course on “Key Concepts in Evolutionary Ecology”, followed by another excellent set of Master students taking our module “Evolution of Behaviour”. 471 kata lagi

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