Tag » Immunology

Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-{beta} Synthesis Induced by Lipopolysaccharide [INNATE IMMUNITY AND INFLAMMATION]

The innate immune response is a central element of the initial defense against bacterial and viral pathogens. Macrophages are key innate immune cells that upon encountering pathogen-associated molecular patterns respond by producing cytokines, including IFN-β. 201 kata lagi

By Alexandros G. Sfakianakis

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [IMMUNE REGULATION]

IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells. 128 kata lagi

By Alexandros G. Sfakianakis